When a predicted mean response on a transformed scale is converted back to its original scale, the predicted mean becomes the predicted median. A correction is applied to the back-transformed prediction so it correctly predicts the mean, rather than the median. This correction may be toggled on/off by clicking Edit > Preferences > Math Analysis > Correct biased predictions of mean.
Use the predicted mean for making inferences and prediction about your process.
D. Miller. Reducing transformation bias in curve fitting. The American Statistician, 38(2):124–126, 1984.