Case Studies and White Papers


Trimming the FAT: Part II

Published: September 2005
Author: Mark Anderson

The first article, "Trimming the FAT out of Experimental Methods," presented arguments against one-factor-at-a-time (OFAT) techniques in favor of multifactor DOE. This follow-up article offers a case study that illustrates how a two-level factorial DOE can reveal a breakthrough interaction. A similar article appeared in OE (Optical Engineering) magazine.

Publication: Optical Engineering

Trimming the FAT out of Experimental Methods

Published: June 2005
Author: Mark Anderson

This introductory article provides compelling reasons to abandon traditional scientific methods that deploy only one factor at a time (OFAT) in favor of multifactor testing techniques known as design of experiments (DOE). Only via DOE can experimenters detect interactions, which often prove to be the key to success.

Publication: Optical Engineering

PCR Process Optimized via Split-Plot DOE

Published: May 2005
Authors: Patrick Whitcomb, Shari Kraber

This paper illustrates the use of design of experiments (DOE) and split-plot design to quickly and effectively determine the factor settings that maximize amplification in a polymerase chain reaction (PCR) experiment.

Publication: 2005 ASQ World Congress

Reducing 300mm Wafer Coating Defects without Compromising Uniformity

Published: May 2005
Author: Carlton Washburn

Via a sequential strategy of experimentation using factorial DOE and response surface methods (RSM), engineers at Brewer Science, a microelectronic materials manufacturer, made breakthrough quality improvements in the production of their 300 mm wafers.

Publication: Semiconductor Manufacturing Magazine

Design of Experiments Training Banishes Purple-Paper Blues

Published: April 2005
Author: Stora Enso

A paper mill used DOE to pre-define the appearance and shade of paper before full production. They discovered an unexpected interaction takes of a new blue-dye with coating formulation containing a starch binder. It turned the paper purple, which did not happen with a latex binder. This episode formed the basis for a DOE-training exercise.

Published: April 2005
Authors: Thomas Erbach, Lisa Fan, Shari Kraber

An innovative blend of hardware, software and the right training in statistical know-how supercharges research automation.

Publication: Quality Digest

Published: February 2005
Author: Charles Zovko

Engineers use mixture design to create thinner, whiter keypad backlighting. A slightly different version was published in Product Design & Development.

Publication: Product Design & Development

Published: February 2005
Author: Stepan Co.

DOE is used in this study demonstrating the versatile compatibility of a unique polyester polyol, PD-90 LV, with both polyester and polyether polyols.

Publication: Adhesives & Sealants Industry

Published: December 2004
Author: Bill Craig

Proper application of solder paste onto a PCb is essential in surface mount assemblies. In this case study DOE was used to understand this process, and ultimately to improve electrical yields.

Publication: Surface Mount Technology

Published: July 2004
Author: Carl Clarke

Engineers solved two perplexing wafer production mysteries using design of experiments (DOE), saving the company $180,000 a year.

Publication: MICRO Magazine (Discontinued)