Case Studies

Items 61 to 75 of 205 total

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  1. Streamwise Porosity Distribution Optimization for Minimizing Wall Interference in a Transonic Wind Tunnel

    January 2009

    Modern Design of Experiments (MDOE) was used to reduce wall interference on wind tunnel measurements, increasing the quality of both the raw data and corrected coefficients.

    Authors: Owen, U. N.
    Publication: Conference
  2. Design of Experiments Demonstrates Robustness of Biopharmaceutical Process

    January 2009

    Diasorin recently used DOE to evaluate the robustness of its process for manufacturing an alpha-1-antitrypsin (AAT) assay.

    Authors: DiaSorin
    Publication:
  3. Optimal Blending of Rayon Fibers via Statistical Design of Experiments (DOE) Tailored for Formulation

    January 2009

    A statistically based design of experiments (DOE) approach developed specifically for mixtures was used to formulate a blend of rayon fibers that produced maximal tampon absorbency.

    Authors: Anderson, Mark J.; Lazic, Zivorad R.
    Publication:
  4. Correcting Low First-Pass Yield

    December 2008

    The Williamette Valley Co. (WVCO) increased manufacturing yield by designing an experiment to simultaneously measure the impact of key factors on critical responses

    Authors: Williamette Valley Co.
    Publication: Quality Magazine
  5. Lean Six Meets Foil Stamping

    October 2008

    This article describes how a six sigma team cut setup time 40% and printing costs 5% at a Taylor Corporation unit using DOE and 33 Kluge presses.

    Originally Published in Graphic Arts Online Oct 1, 2008

    Authors: Taylor Corp.
    Publication: Graphic Arts Online
  6. Response Surface Methods (RSM) Achieve Design for Six Sigma (DFSS) Goals for Medical Device Manufacturing

    October 2008

    Engineers at a major medical device manufacturer used RSM to successfully model a key process for their flagship product. The RSM model then became the foundation for development of robust specifications to ensure quality at six sigma levels.

    Authors: Anderson, Mark
    Publication:
  7. Design of Experiments Reduces Rubber Scrap by 90%

    September 2008

    A custom rubber molder used DOE to uncover a combination of material selection and manufacturing protocol that created unacceptable results. Armed with this process knowledge, they achieved a breakthrough quality improvements.

    Authors: Anderson, Mark J.
    Publication: Rubber & Plastics News
  8. Design of Experiments Helps Reduce Time to Remove Aerospace Coatings (See page 21)

    September 2008

    Aerochem Inc. used DOE to develop a chemical paint remover that would remove the coating in less than 2 hours.

    Authors: Aerochem
    Publication: Aerospace Engineering & Manufacturing
  9. Optimizing Design of Experiments for Fluid Bed Coating

    September 2008

    Upsher-Smith Laboratories used Design of Experiments to optimize a fluid bed coating process that was producing inconsistent results.

    Authors: Upsher-Smith
    Publication: Pharmaceutical Manufacturing
  10. DOE Eliminates Defects

    August 2008

    A major Tier 1 automotive supplier wanted to improve the already high level of quality in their manufacturing process welding nuts to a metal seat frame. They contacted Middle Tennessee State University (MTSU) and requested a design of experiments (DOE) study to determine root causes of torque failures and areas of improvement.

    Authors: MTSU/Johnson Controls
    Publication: Quality Magazine
  11. Mixture Design of Experiments (DOE) for Optimal Plasma Etch

    August 2008

    This article demonstrates how to uncover "sweet spots" where multiple fab-process specifications can be met in a most desirable way.

    Authors: Anderson, Mark
    Publication: Fab Engineering & Operations
  12. Army Case Study: Benet Uses DOE to Reduce Time Required to Optimize Complex Design

    June 2008

    Design of experiments was used for a series of computer simulations to design a new generation of muzzle brakes. DOE saves time by reducing the amount of simulations required and makes it possible to optimize.

    Authors: U.S. Army Benet Laboratories
    Publication: Military Embedded Systems
  13. Pharmaceutical Manufacturer Increases Yield with Response Surface Methods

    May 2008

    MannKind Corporation used designed experiments to identify and optimize critical process variables involved in producing a small molecule substrate for use in pulmonary drug delivery.

    Authors: MannKind
    Publication: Pharmaceutical Processing
  14. Tabletop Hockey Meets Goals for Teaching Experimental Design

    April 2008

    In this mini-paper, Mark Anderson details an in-class experiment illustrating the power of two-level factorial design. Also learn how to shoot a wicked slap shot!"

    Authors: Anderson, Mark
    Publication: Statistics Division Newsletter
  15. Statistical Design of Experiments on Fabrication of Starch Nanoparticles - A Case Study for Application of Response Surface Methods

    April 2008

    This paper use the fabrication of nanoparticles as an example for showing a statistically-rigorous approach to design and analysis of pharmaceutical experiments.

    Authors: Bukhari, Nadeem Irfan et. al.
    Publication:

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